(Pyr-6,Pro9)-Substance P (6-11) contains pyroglutamate at residue 6 and proline at residue 9, creating a sterically constrained signaling fragment. These substitutions enhance backbone rigidity and modulate hydrophobic interactions. Its short sequence assists in determining minimal motifs for tachykinin recognition. Researchers employ it in high-resolution structural and receptor-binding studies.
CAT No: S09047
3. Immune responses to homocitrulline-and citrulline-containing peptides in rheumatoid arthritis
4. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
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