Rev4

Reverse peptide of indolicidin (Rev4), a 13-residue peptide based on the sequence of indolicidin1.Indolicidin, a member of the cathelicidin protein family, is a 13-residue cationic, antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils2. The synthetic peptide Rev4 has been shown to possess both strong antimicrobial and protease inhibitory activities in vitro.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: AF3348

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.W/Mr.
1907.4
Sequence
One Letter Code: RRWPWWPWKWPLI
Three Letter Code: H-Arg-Arg-Trp-Pro-Trp-Trp-Pro-Trp-Lys-Trp-Pro-Leu-Ile-OH
Long-term Storage Conditions
Rev4 antimicrobial peptide is freely soluble in H2O
References
1. Xing H. et al., Planta, 223 (5),1024-32 (2005)
2. Ösapay, K. et al. J. Biol. Chem. 275, 12017 (2000)
3. Li Q. et al., Peptides 23(1),1-6 (2002)

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