RH-Oligopeptide-1 is a recombinant human peptide identical to epidermal growth factor (EGF), produced via biotechnology for cosmetic applications. It is valued in formulation for its role in supporting skin conditioning and maintaining a healthy appearance. Suitable for use in a variety of topical products, RH-Oligopeptide-1 is compatible with standard cosmetic matrices and aligns with global regulatory guidelines for cosmetic ingredients.
CAT No: CPC1721
CAS No:62253-63-8
Synonyms/Alias:RHEGF;NMEGF;HOMG4;Epidermal Growth Factor;
Mechanism of Action (MOA)
RH-Oligopeptide-1, a recombinant human epidermal growth factor (EGF) mimetic peptide, interacts with epidermal growth factor receptors (EGFR) on the cell surface. This binding initiates intracellular signaling cascades, including the MAPK/ERK and PI3K/Akt pathways, which are associated with cellular processes such as proliferation and differentiation. The peptide's activity supports the modulation of epidermal cell communication and contributes to the maintenance of healthy-appearing skin.
RH-Oligopeptide-1 can be incorporated into a variety of cosmetic formulations to enhance product offerings.
- Suitable for use in facial serums and ampoules- Can be added to lightweight emulsions such as lotions and creams- Compatible with sheet masks and hydrogel patches- May be included in eye care products- Appropriate for leave-on and rinse-off formulations- Recommended for pre- and post-sun care products
3. Cationic cell-penetrating peptides are potent furin inhibitors
5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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