rh-Polypeptide-1 is a recombinant human peptide produced via controlled biotechnological processes. Recognized for its biomimetic properties, this ingredient is designed to support skin conditioning and maintenance in advanced cosmetic formulations. Its compatibility with a wide range of delivery systems makes it suitable for anti-aging, moisturizing, and skin care applications where enhanced skin appearance and texture are desired. rh-Polypeptide-1 is compliant with global cosmetic regulations.
Mechanism of Action (MOA)
rh-Polypeptide-1, a recombinant human oligopeptide, is designed to mimic naturally occurring signaling peptides involved in skin physiology. Upon topical application, it interacts with cell surface receptors and may support cellular communication pathways, including those related to the extracellular matrix. This peptide is known to participate in the modulation of biochemical signals that influence keratinocyte and fibroblast activity, contributing to the maintenance of a balanced skin environment.
rh-Polypeptide-1 is suitable for incorporation into a variety of cosmetic formulations.
- Facial serums and ampoules- Moisturizing creams and lotions- Eye contour products- Sheet masks and leave-on treatments- Lightweight emulsions and gels- Post-procedure cosmetic care products
1. TMEM16F and dynamins control expansive plasma membrane reservoirs
3. High fat diet and GLP-1 drugs induce pancreatic injury in mice
4. The spatiotemporal control of signalling and trafficking of the GLP-1R
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
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