Risuteganib

Name: Risuteganib
Brand: Creative Peptides
SKU: R1894
Availability: MadeToOrder

Risuteganib, also known as ALG1001, is an anti-integrin that downregulates oxidative stress and restores homeostasis, and targets three integrin receptors that are implicated in dry age-related macular degeneration (AMD) in order to restore homeostasis in the retina.

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CAT No: R1894

CAS No: 1307293-62-4

Synonyms/Alias: Risuteganib;Luminate;1307293-62-4;ALG1001;ALG-1001;Risuteganib [USAN];123DNA66IA;UNII-123DNA66IA;GLY-ARG-GLY-CYA-THR-PRO;Risuteganib (USAN);(2S)-1-[(2S,3R)-2-[[(2R)-2-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-sulfopropanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid;Glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-L-proline;L-Proline, glycyl-L-arginylglycyl-3-sulfo-L-alanyl-L-threonyl-;Risuteganib [WHO-DD];RISUTEGANIB [INN];ALG1001 (Risuteganib);ALG-1001 HEXAPEPTIDE;CHEMBL4297529;SCHEMBL19410626;HY-P1930;DB14911;DA-70689;CS-0019633;D11436;

Chemical Name: (2S)-1-[(2S,3R)-2-[[(2R)-2-[[2-[[(2S)-2-[(2-aminoacetyl)amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]-3-sulfopropanoyl]amino]-3-hydroxybutanoyl]pyrrolidine-2-carboxylic acid; glycyl-L-arginyl-glycyl-L-cysteyl-L-threonyl-L-proline

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Specification Technical Data Publications Customer reviews and Q&A

M.F/Formula	C22H39N9O11S
M.W/Mr.	637.7
Sequence	One Letter Code:GRGXTP Three Letter Code:H-Gly-Arg-Gly-Cys(O3H)-Thr-Pro-OH
Appearance	Solid powder

Size	6
Long-term Storage Conditions	Soluble in DMSO
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
InChI	InChI=1S/C22H39N9O11S/c1-11(32)17(20(37)31-7-3-5-14(31)21(38)39)30-19(36)13(10-43(40,41)42)29-16(34)9-27-18(35)12(28-15(33)8-23)4-2-6-26-22(24)25/h11-14,17,32H,2-10,23H2,1H3,(H,27,35)(H,28,33)(H,29,34)(H,30,36)(H,38,39)(H4,24,25,26)(H,40,41,42)/t11-,12+,13+,14+,17+/m1/s1
InChI Key	MYZAXBZLEILEBR-RVFOSREFSA-N
Canonical SMILES	CC(C(C(=O)N1CCCC1C(=O)O)NC(=O)C(CS(=O)(=O)O)NC(=O)CNC(=O)C(CCCN=C(N)N)NC(=O)CN)O

1. High fat diet and GLP-1 drugs induce pancreatic injury in mice

2. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

3. Exosomes-mediated Transfer of miR-125a/b in Cell-to-cell Communication: A Novel Mechanism of Genetic Exchange in the Intestinal Microenvironment

4. Glucagonlike peptide 2 analogue teduglutide: stimulation of proliferation but reduction of differentiation in human Caco-2 intestinal epithelial cells

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