(Sar1)-Angiotensin II

(Sar¹)-Angiotensin II is a stabilized analog used to explore N-terminal structural constraints in angiotensin receptor interactions. Its sarcosine substitution influences backbone flexibility and binding geometry. Researchers use it to evaluate minimal motifs driving signal initiation. The peptide supports high-resolution analysis of angiotensin-family ligands.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: A15093

CAS No:51833-69-3

Synonyms/Alias:(Sar1)-Angiotensin II;51833-69-3;CHEMBL216061;Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH;MFCD00167493;(Sar 1)-Angiotensin II;HY-P3138;BDBM50011973;AKOS040754865;DA-59712;FS108527;MS-31855;CS-0148150;G12437;Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH; H-(Sar)RVYIHPF-OH;(Sar1)-Angiotensin II (H-Sar-DL-Arg-L-Val-L-Tyr-L-Ile-L-His-L-Pro-L-Phe-OH);(2S)-2-[[(2S)-1-[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-(diaminomethylideneamino)-2-[[2-(methylamino)acetyl]amino]pentanoyl]amino]-3-methylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid;

Custom Peptide Synthesis
cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C49H71N13O10
M.W/Mr.
1002.2
Sequence
One Letter Code:GRVYIHPF
Three Letter Code:H-Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Source#
Synthetic
InChI
InChI=1S/C49H71N13O10/c1-6-29(4)41(46(69)58-36(24-32-25-53-27-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)40(28(2)3)60-42(65)34(56-39(64)26-52-5)14-10-20-54-49(50)51/h7-9,12-13,16-19,25,27-29,34-38,40-41,52,63H,6,10-11,14-15,20-24,26H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,50,51,54)/t29-,34-,35-,36-,37-,38-,40-,41-/m0/s1
InChI Key
WCYZYYURIHACQW-KOTWUFNXSA-N

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