Suc-Ala-Ala-Pro-Nva-pNA substitutes norvaline at the P1 position, altering the shape and hydrophobicity of the active-site interface. Structural similarity to related substrates enables fine-tuning of specificity profiles. pNA release reports on catalytic efficiency. Researchers apply it in comparative protease assays and active-site mapping.
1. The spatiotemporal control of signalling and trafficking of the GLP-1R
3. Emu oil in combination with other active ingredients for treating skin imperfections
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