Tat-NR2B9c TFA, a noteworthy biomedical product, manifests as a potential panacea for intricate neurological maladies, most notably Alzheimer's disease. Its inception delineates a peptide-based composition diligently engineered to discerningly obstruct the NR2B subcomponent of N-methyl-D-aspartate (NMDA) receptors, intrinsically entangled in synaptic plasticity and the foundation of memory. Encouragingly, Tat-NR2B9c TFA exhibits auspicious propensities towards attenuating excitotoxicity while concurrently ameliorating cognitive faculties.
CAT No: GR2150
CAS No:1834571-04-8
Synonyms/Alias:Tat-NR2B9c;500992-11-0;Nerinetide;Tat-NR2B9c TFA;NA-1;FN023;1834571-04-8;Nerinetida;Nerinetide [USAN];Tat NR2B9c;UNII-D45TI2TWMA;D45TI2TWMA;Tat-NR2Bct TFA;NA-1 TFA;GTPL12332;FN-023;WHO 10857;AKOS040740169;AS-82902;DA-58297;DA-58298;D84054;L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L- glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-L-valine;L-Valine, L-tyrosylglycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L- glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-lysyl-L-leucyl-L-seryl-L-seryl-L-isoleucyl-L-alpha-glutamyl-L-seryl-L-alpha-aspartyl-;
Chemical Name:(4S)-4-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[(2S)-6-amino-2-[[(2S)-2-[[2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]acetyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]hexanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-oxopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]-5-carbamimidamidopentanoyl]amino]hexanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]amino]-3-hydroxypropanoyl]amino]-3-methylpentanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
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