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Tetrapeptide-4

Tetrapeptide-4 is a synthetic peptide composed of four amino acids, designed for use in cosmetic formulations targeting skin care applications. Its structure enables support of the skin's natural barrier function and contributes to the maintenance of overall skin condition. Suitable for a range of product types, Tetrapeptide-4 is compatible with global cosmetic regulations and can be incorporated into serums, creams, and other topical formulations.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CPAG-001

Synonyms/Alias:tetrapeptide-4;960608-16-6;GEPG;COLLASYN-4GG;GLY-GLU-PRO-GLY;COLLASYN 4 GG;S9N5X165MO;HY-P5237;DA-58450;CS-0863814;Q27289090

Chemical Name:(4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-(carboxymethylcarbamoyl)pyrrolidin-1-yl]-5-oxopentanoic acid

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C14H22N4O7
M.W/Mr.
358.35
Sequence
One Letter Code:GEPG
Three Letter Code:H-Gly-Glu-Pro-Gly-OH

Mechanism of Action (MOA)

Tetrapeptide-4 is a synthetic signaling peptide composed of four amino acids. It is designed to interact with skin cells by modulating cellular communication pathways, particularly those involved in the extracellular matrix. By supporting the expression of key proteins such as collagen and fibronectin, Tetrapeptide-4 helps optimize the skin's structural environment. This peptide may also influence the activity of enzymes linked to matrix turnover, contributing to enhanced skin condition and resilience.

Tetrapeptide-4 can be incorporated into various cosmetic formulations to enhance product versatility and sensory appeal.

- Suitable for use in facial serums and emulsions
- Compatible with water-based gels and lotions
- Can be added to eye contour creams
- Appropriate for lightweight daily moisturizers
- Integrates well into sheet masks and leave-on treatments
- May be included in targeted care products

InChI
InChI=1S/C14H22N4O7/c15-6-10(19)17-8(3-4-11(20)21)14(25)18-5-1-2-9(18)13(24)16-7-12(22)23/h8-9H,1-7,15H2,(H,16,24)(H,17,19)(H,20,21)(H,22,23)/t8-,9-/m0/s1
InChI Key
SCAKQYSGEIHPLV-IUCAKERBSA-N
Canonical SMILES
C1CC(N(C1)C(=O)C(CCC(=O)O)NC(=O)CN)C(=O)NCC(=O)O
Isomeric SMILES
C1C[C@H](N(C1)C(=O)[C@H](CCC(=O)O)NC(=O)CN)C(=O)NCC(=O)O

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