TFFH is a fluorinated amino acid derivative bearing a trifluoromethyl-substituted side chain and an amino acid backbone that contains both amino and carboxyl functional groups. The presence of the electron-withdrawing fluorinated substituent imparts distinct polarity and carbon-fluorine bond character relative to non-fluorinated analogues, enabling the molecule to function as a chemically modified amino acid building block for labeling or structure-property studies. TFFH is used in peptide and amino acid derivative synthesis and in analytical or chemical biology workflows where fluorinated functionality is employed to support incorporation into larger constructs or to provide a spectroscopic/chemical handle for detection and characterization.
CAT No: CP26463
CAS No:164298-23-1
Synonyms/Alias:164298-23-1;TFFH;Fluoro-N,N,N',N'-tetramethylformamidiniumhexafluorophosphate;N-((Dimethylamino)fluoromethylene)-N-methylmethanaminiumhexafluorophosphate(V);Tetramethylfluoroformamidiumhexafluorophosphate;N,N,N',N'-Tetramethylfluoroformamidiniumhexafluorophosphate;AC1MCOWF;ACMC-209dqu;SCHEMBL789737;520330_ALDRICH;C5H12FN2.F6P;47440_FLUKA;CTK0H6612;MolPort-000-006-311;ZAVXOOLKAGPJPI-UHFFFAOYSA-N;ANW-22084;CT-088;SBB102764;AKOS015909557;LS40001;RL02107;VZ36934;AK158837;AN-30920;BC204238
3. Cationic cell-penetrating peptides are potent furin inhibitors
5. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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