Threo-DL-β-Hydroxynorvaline is a non-proteinogenic β-hydroxy amino acid derivative featuring a five-carbon (norvaline) backbone with a hydroxyl substituent at the β-position and a threo relative configuration within the β-hydroxy stereochemical relationship, supplied as a DL mixture. The molecule contains both an amino group and a carboxyl group, enabling formation of amino acid salts and peptide-coupling intermediates, while the β-hydroxyl side chain provides an additional hydrogen-bonding and polarity handle for chemical derivatization. In synthetic peptide chemistry and chemical biology, it is used to introduce β-hydroxy functionality into peptide analogues and to support structure-activity studies, crosslinking or conjugation strategies, and analytical method development involving β-hydroxy amino acid motifs.
CAT No: CP07403
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