Threo-3-Methylglutamic acid is a threo-configured, non-proteinogenic glutamic acid derivative bearing an extra methyl substituent at the 3-position of the side chain, which modifies the steric and conformational properties relative to unmodified glutamic acid. The molecule contains an α-amino group and a carboxylic acid at the α-position, along with a second side-chain carboxyl group characteristic of glutamate-like amino acids, and it is available as the free amino acid form suitable for direct incorporation into chemical transformations targeting amino acid functionality. In synthetic and chemical biology workflows, it is used as a defined amino acid building block for preparing modified peptides and peptidomimetics, for structure-activity studies where altered side-chain geometry is required, and for analytical method development involving glutamate analog standards.
CAT No: CP08202
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