Tos-L-Phe-OH is an L-phenylalanine derivative in which the amino group is protected as a tosyl (Ts) sulfonamide while retaining the free carboxylic acid functionality. The molecule contains an aromatic benzyl side chain characteristic of phenylalanine, and its Ts-protected nitrogen provides sulfonamide stabilization and chemoselective behavior by reducing the nucleophilicity of the amino group relative to unprotected amino acids. Tos-L-Phe-OH is used as a protected amino acid building block for preparing peptide-related intermediates and for controlled stepwise assembly of amino acid sequences in solution-phase or solid-phase synthesis workflows where the carboxyl group and protected amine must be differentiated.
CAT No: CP25324
CAS No:13505-32-3
Synonyms/Alias:13505-32-3;N-(p-Toluenesulfonyl)-L-phenylalanine;n-p-tosyl-l-phenylalanine;Tosyl-L-phenylalanine;(S)-2-(4-Methylphenylsulfonamido)-3-phenylpropanoicacid;N-((4-Methylphenyl)sulfonyl)-L-phenylalanine;N-[(4-methylphenyl)sulfonyl]-L-phenylalanine;Tos-Phe;Tos-Phe-OH;AmbotzTAA1511;n-tosyl-l-phenylalanine;AC1L40TG;AC1Q2LI0;AC1Q6VF9;SCHEMBL697477;CHEMBL3275993;CTK1B7564;ZINC53903;CGRCVIZBNRUWLY-HNNXBMFYSA-N;MolPort-001-792-340;N-p-toluenesulfonyl-L-phenylalanine;34635-34-2;ANW-19740;AR-1K8133;EBD191889
Chemical Name:N-alpha-p-Toluolsulfonyl-L-phenylalanine
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