Trt-Glu(OtBu)-OH · DCHA is a protected glutamic acid derivative in which the side-chain carboxyl group is masked as a tert-butyl ester (Glu(OtBu)) while the α-amino group is protected by a trityl (Trt) group, yielding a protected amino acid bearing a free carboxylic acid at the α-position. The molecule therefore contains a Trt-protected amine, an α-carboxylic acid, and a tert-butyl ester functionality on the side-chain carboxyl, and it is provided as a DCHA salt form (dicyclohexylamine), which affects its handling and crystallization behavior without changing the covalent protecting groups. This protected amino acid is used as a stepwise building block for peptide synthesis and related amino acid coupling workflows, where the orthogonal protection pattern supports controlled deprotection and chemoselective formation of amide bonds.
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