Veldoreotide

Veldoreotide, a remarkable synthetic somatostatin analog widely employed in the field of biomedicine, emerges as an imperative therapeutic agent bestowed with exquisite properties. Ostensibly tailored to combat acromegaly, an endocrine anomaly resultant from the relentless surge in growth hormone secretion, Veldoreotide orchestrates its profound efficacy through the judicious inhibition of growth hormone release. Through such a meticulously orchestrated mechanism, the subject in question undeniably manifests potential in permeating symptomatic alleviation, targeting the resolution of presumably incapacitating manifestations encompassing the elongation of appendages, including hands and feet, as well as pertinent facial metamorphoses.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: R1984

CAS No:252845-37-7

Synonyms/Alias:Veldoreotide;Somatoprim;252845-37-7;Veldoreotide [USAN];COR-005;PTR 3173;UNII-1Z83587HBN;1Z83587HBN;VELDOREOTIDE [INN];DG 3173;VELDOREOTIDE [WHO-DD];PTR-3173;DG3173;2-[(3S,6S,9S,12R,15S,18S)-9-(4-Aminobutyl)-3,18-dibenzyl-6-[(1R)-1-hydroxyethyl]-12,15-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,25-octaoxo-1,4,7,10,13,16,19,24-octazacyclooctacos-1-yl]acetamide;DG-3173;veldoreotida;2-[(3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-6-(1-hydroxyethyl)-12,15-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,25-octaoxo-3,18-bis(phenylmethyl)-1,4,7,10,13,16,19,24-octazacyclooctacos-1-yl]acetamide;GLYCINAMIDE, N-(4-AMINO-1-OXOBUTYL)-L-PHENYLALANYL-L-TRYPTOPHYL-D-TRYPTOPHYL-L-LYSYL-L-THREONYL-L-PHENYLALANYL-N2-(3-CARBOXYPROPYL)-, (7->1)-LACTAM;N4.1-(2-AMINO-2-OXOETHYL)-CYCLO(4-AMINOBUTANOYL-4-AMINOBUTANOYL-L-PHENYLALANYL-L-TRYPTOPHYL-D-TRYPTOPHYL-L-LYSYL-L-THREONYL-L-PHENYLALANYL);veldoreotidum;2-((3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3,18-dibenzyl-6-((1R)-1-hydroxyethyl)-12,15-bis((1H-indol-3-yl)methyl)-2,5,8,11,14,17,20,25-octaoxo-1,4,7,10,13,16,19,24-octaazacyclooctacosan-1-yl)acetamide;2-((3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-6-(1-hydroxyethyl)-12,15-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,25-octaoxo-3,18-bis(phenylmethyl)-1,4,7,10,13,16,19,24-octazacyclooctacos-1-yl)acetamide;2-[(3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3,18-dibenzyl-6-[(1R)-1-hydroxyethyl]-12,15-bis[(1H-indol-3-yl)methyl]-2,5,8,11,14,17,20,25-octaoxo-1,4,7,10,13,16,19,24-octaazacyclooctacosan-1-yl]acetamide;GTPL8487;GLXC-20851;EX-A7913;HY-P0024;DB12777;DA-78857;CS-0012831;Q27253298;

Chemical Name:2-[(3S,6S,9S,12R,15S,18S)-9-(4-aminobutyl)-3,18-dibenzyl-6-[(1R)-1-hydroxyethyl]-12,15-bis(1H-indol-3-ylmethyl)-2,5,8,11,14,17,20,25-octaoxo-1,4,7,10,13,16,19,24-octazacyclooctacos-1-yl]acetamide

Custom Peptide Synthesis
cGMP Peptide
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  • Drug master files (DMF) filing
M.F/Formula
C60H74N12O10
M.W/Mr.
1123.3
InChI
InChI=1S/C60H74N12O10/c1-37(73)54-59(81)70-50(31-39-18-6-3-7-19-39)60(82)72(36-51(62)74)29-15-26-52(75)63-28-14-25-53(76)66-47(30-38-16-4-2-5-17-38)56(78)68-49(33-41-35-65-45-23-11-9-21-43(41)45)58(80)69-48(32-40-34-64-44-22-10-8-20-42(40)44)57(79)67-46(55(77)71-54)24-12-13-27-61/h2-11,16-23,34-35,37,46-50,54,64-65,73H,12-15,24-33,36,61H2,1H3,(H2,62,74)(H,63,75)(H,66,76)(H,67,79)(H,68,78)(H,69,80)(H,70,81)(H,71,77)/t37-,46+,47+,48-,49+,50+,54+/m1/s1
InChI Key
ABFNTRQPWNXUHA-VEVJRHMJSA-N
Canonical SMILES
CC(C1C(=O)NC(C(=O)N(CCCC(=O)NCCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CNC5=CC=CC=C54)CC6=CC=CC=C6)CC(=O)N)CC7=CC=CC=C7)O
Isomeric SMILES
C[C@H]([C@H]1C(=O)N[C@H](C(=O)N(CCCC(=O)NCCCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](C(=O)N[C@H](C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CNC5=CC=CC=C54)CC6=CC=CC=C6)CC(=O)N)CC7=CC=CC=C7)O

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