Z-Asp(OtBu)-OMe is a protected aspartic acid derivative featuring an aspartate side chain bearing a tert-butyl ester (Asp(OtBu)) and a benzyloxycarbonyl (Z) protecting group on the α-amino functionality, with the carboxyl terminus converted to a methyl ester (OMe). The molecule contains both the Z-carbamate and ester carbonyls, which mask the free amino and carboxyl groups to control chemoselectivity during stepwise assembly of peptide frameworks, while the tert-butyl ester on the side chain provides orthogonal protection relative to the α-carboxyl methyl ester. Z-Asp(OtBu)-OMe is employed as an amino acid building block for peptide synthesis and for preparing aspartate-containing intermediates where protected functional-group patterns are required for controlled coupling and downstream deprotection strategies.
CAT No: CP00438
CAS No:63327-57-1
Synonyms/Alias:Z-L-aspartic acid β-tert.butyl ester α-methyl ester;
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More