Z-D-Glu-OMe is a protected, stereodefined amino acid methyl ester featuring the D configuration at the glutamate α-carbon and a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality, with the side chain containing a terminal γ-carboxylate esterified as a methyl ester. The molecule contains an ester carbonyl in the OMe group and a second ester carbonyl in the γ-position, while the Z carbamate masks the α-amino group and reduces undesired amine reactivity during handling and coupling steps. Z-D-Glu-OMe is used as a glutamate building block and peptide intermediate in protected amino acid synthesis, enabling controlled incorporation of a glutamate residue motif into peptide chains and supporting downstream deprotection and functionalization strategies for side-chain carboxyl chemistry.
CAT No: CP26916
CAS No:26566-11-0
Synonyms/Alias:z-d-glu-ome;26566-11-0;D-Glutamicacid,N-[(phenylmethoxy)carbonyl]-,1-methylester;AC1OE2I7;SCHEMBL2777678;MolPort-016-580-305;ZINC1873093;2388AB;AKOS016003147;AJ-32207;AK-85730;FT-0696179;ST24050365;N-(Benzyloxycarbonyl)-D-glutamicacid1-methylester;(4R)-5-methoxy-5-oxo-4-(phenylmethoxycarbonylamino)pentanoicacid
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