Z-D-Glu-OMe

Z-D-Glu-OMe is a protected, stereodefined amino acid methyl ester featuring the D configuration at the glutamate α-carbon and a benzyloxycarbonyl (Z, Cbz) protecting group on the amino functionality, with the side chain containing a terminal γ-carboxylate esterified as a methyl ester. The molecule contains an ester carbonyl in the OMe group and a second ester carbonyl in the γ-position, while the Z carbamate masks the α-amino group and reduces undesired amine reactivity during handling and coupling steps. Z-D-Glu-OMe is used as a glutamate building block and peptide intermediate in protected amino acid synthesis, enabling controlled incorporation of a glutamate residue motif into peptide chains and supporting downstream deprotection and functionalization strategies for side-chain carboxyl chemistry.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP26916

CAS No:26566-11-0

Synonyms/Alias:z-d-glu-ome;26566-11-0;D-Glutamicacid,N-[(phenylmethoxy)carbonyl]-,1-methylester;AC1OE2I7;SCHEMBL2777678;MolPort-016-580-305;ZINC1873093;2388AB;AKOS016003147;AJ-32207;AK-85730;FT-0696179;ST24050365;N-(Benzyloxycarbonyl)-D-glutamicacid1-methylester;(4R)-5-methoxy-5-oxo-4-(phenylmethoxycarbonylamino)pentanoicacid

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M.F/Formula
C14H17NO6
M.W/Mr.
295.29
Size
1 g;5 g;
InChI
1S/C14H17NO6/c1-20-13(18)11(7-8-12(16)17)15-14(19)21-9-10-5-3-2-4-6-10/h2-6,11H,7-9H2,1H3,(H,15,19)(H,16,17)/t11-/m1/s1
InChI Key
BGMCTGARFXPQML-LLVKDONJSA-N
Canonical SMILES
COC(=O)C(CCC(=O)O)NC(=O)OCC1=CC=CC=C1

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