Z-Glu(OBzl)-OSu

Z-Glu(OBzl)-OSu contains a glutamic acid side chain bearing an O-benzyl ester (OBzl) and a Z (benzyloxycarbonyl) protecting group on the amino functionality, with the carboxyl terminus converted to an N-succinimidyl ester (OSu) that activates the acid for acyl transfer. The molecule therefore presents a protected α-amino group, an esterified γ-carboxyl side chain, and an activated carboxyl group as the OSu leaving group, enabling chemoselective coupling while suppressing unprotected amide formation at the α-position. Z-Glu(OBzl)-OSu is used as an amino acid derivative in peptide synthesis and in bioconjugation workflows where an activated glutamate residue is required for forming amide bonds under conditions compatible with the Z and benzyl ester protecting groups.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP27350

CAS No:67413-34-7

Synonyms/Alias:Z-GLU(OBZL)-OSU;67413-34-7;7903AH;KM1094;ZINC71788251

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M.F/Formula
C24H24N2O8
M.W/Mr.
468.47
Size
1 g;5 g;25 g;
InChI
1S/C24H24N2O8/c27-20-12-13-21(28)26(20)34-23(30)19(25-24(31)33-16-18-9-5-2-6-10-18)11-14-22(29)32-15-17-7-3-1-4-8-17/h1-10,19H,11-16H2,(H,25,31)/t19-/m0/s1
InChI Key
FSHGVTPZOIGKTM-IBGZPJMESA-N
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)C(CCC(=O)OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

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