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Z-Gly-ONp

Z-Gly-ONp is a protected glycine derivative in which the amino group is carbobenzyloxy (benzyloxycarbonyl, Z) protected and the carboxyl group is converted to an ONp ester (p-nitrophenyl ester), forming a peptide-coupling-ready intermediate. The molecule contains the Z-protected α-amino functionality and an esterified carboxylate bearing the p-nitrophenyl leaving group, while the glycine side chain is a methylene substituent, and no stereochemical configuration is specified in the product name. Z-Gly-ONp is used in peptide synthesis and related amide-bond formation workflows as an activated amino acid ester that can undergo nucleophilic acyl substitution with amines under appropriate conditions, and the p-nitrophenyl group also supports monitoring of reaction progress in analytical contexts where p-nitrophenol release is detectable.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25468

CAS No:1738-86-9

Synonyms/Alias:1738-86-9;N-Carbobenzoxyglycine4-NitrophenylEster;Z-Gly-ONp;N-Carbobenzoxyglycinep-nitrophenylester;N-Benzyloxycarbonylglycine4-nitrophenylester;N-alpha-Benzyloxycarbonyl-Glyp-nitrophenylester;N-Cbz-glycine4-NitrophenylEster;EINECS217-097-2;4-Nitrophenyl2-(((benzyloxy)carbonyl)amino)acetate;NSC405051;BRN1916980;GLYCINE,N-CARBOXY-,N-BENZYLESTER,p-NITROPHENYLESTER;ST50410459;4-NitrophenylN-((phenylmethoxy)carbonyl)glycinate;4-nitrophenyl2-{[(benzyloxy)carbonyl]amino}acetate;N-CBZ-GLYCINE-P-NITROPHENYLESTER;Glycine,N-((phenylmethoxy)carbonyl)-,4-nitrophenylester;Glycine,N-[(phenylmethoxy)carbonyl]-,4-nitrophenylester;p-NitrophenylZ-glycinate;CHEMBL12788;Z-glycine4-nitrophenylester;p-Nitrophenylcarbobenzoxyglycine;AC1L269O;SCHEMBL1803004;Jsp003558

Chemical Name:N-alpha-Benzyloxycarbonyl-glycine p-nitrophenyl ester

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M.F/Formula
C16H14N2O6
M.W/Mr.
330,3 g/mole
Size
25 g;100 g;
InChI
1S/C16H14N2O6/c19-15(24-14-8-6-13(7-9-14)18(21)22)10-17-16(20)23-11-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,20)
InChI Key
LHFNPUGRSYOPLF-UHFFFAOYSA-N
Canonical SMILES
C1=CC=C(C=C1)COC(=O)NCC(=O)OC2=CC=C(C=C2)[N+](=O)[O-]

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