Z-Homocit-OH contains a homocitamic acid (homocitrate) amino acid skeleton bearing a side chain with two carboxylate functionalities and an amino group, with the alpha-carboxylic acid present as a free acid (OH) to define it as an amino acid derivative rather than an unprotected free amino acid. The N-terminus is protected as a benzyloxycarbonyl (Z, Cbz) carbamate, leaving the alpha-amino functionality masked while the carboxyl groups remain available for salt formation, coupling, or analytical derivatization; stereochemistry is not specified in the provided name. Z-Homocit-OH is used in peptide and amino-acid derivative synthesis as a protected, side-chain-functionalized building block where the Cbz group supports chemoselective handling of the amino functionality and the dicarboxylate side chain provides reactive handles for structure-activity studies, conjugation, and preparation of more complex amino acid and peptide analogues.
CAT No: CP27229
CAS No:57533-91-2
Synonyms/Alias:(3S)-3-hydroxy-D-asparticacid;CHEMBL568192;(2R,3S)-2-amino-3-hydroxybutanedioicacid;CHEBI:60893;D-erythro-3-hydroxyasparticacid;erythro-3-hydroxy-D-asparticacid;erythro-beta-hydroxy-D-asparticacid;(2R,3S)-2-amino-3-hydroxysuccinicacid;5753-30-0;D-erythro-beta-hydroxyaspartate;(2R,3S)-2-AMINO-3-HYDROXY-SUCCINICACID;Lopac-H-2775;AC1O7G3M;SCHEMBL5019049;CTK5A7014;ZINC3875091;BDBM50378533;D-Asparticacid,3-hydroxy-,(3S)-;NCGC00015504-01;AM009644;FT-0690419;C19838;I14-37326
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