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Z-L-Arg(Pbf)-OH*CHA

Z-L-Arg(Pbf)-OH*CHA contains the amino acid side chain of L-arginine with a guanidinium functionality, where the side chain is protected as a Pbf (2,2,4,6,7-pentamethylbenzene sulfonyl) derivative and the alpha-amino group is protected by a Z (benzyloxycarbonyl) carbamate, while the carboxyl group is present as a free acid. The molecule bears the characteristic arginine guanidinium motif in protected form and includes the Z and Pbf protecting groups to control chemoselectivity during peptide coupling and to suppress undesired side reactions from the strongly basic side chain. Z-L-Arg(Pbf)-OH*CHA is used as a protected amino acid building block for stepwise peptide synthesis and for preparing arginine-containing peptide or peptidomimetic structures where selective deprotection and incorporation of the arginine residue are required.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25551

CAS No:200190-89-2

Synonyms/Alias:Z-Arg(Pbf)-OHcyclohexylammoniumsalt;Z-D-Arg(Pbf)-OH*CHA;200190-89-2;z-arg(pbf)-oh.cha;200191-00-0;Z-Arg(Pbf)-OHHA;Z-D-Arg(Pbf)-OH.CHA;Z-Arg(Pbf)-OH.CHA;96970_ALDRICH;96970_FLUKA;CTK8E9962;MolPort-003-939-980;Z-Arg(Pbf)-OHcyclohexylaminesalt;CZ-098;RT-016303;FT-0648847;ST24050359;K-5847;Z-Arg(Pbf)-OHinvertedexclamationmarkcurrencyCHA;N|A-Z-N|O-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininecyclohexylammoniumsalt;Nalpha-Z-Nomega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininecyclohexylaminesalt;Nalpha-Z-Nomega-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-argininecyclohexylammoniumsalt

Chemical Name:N-alpha-Benzyloxycarbonyl-N-2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl-L-arginine cyclohexylamine

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M.F/Formula
C33H49N5O7S
M.W/Mr.
560,67*99,18 g/mole
Size
1 g;5 g;
InChI
1S/C27H36N4O7S.C6H13N/c1-16-17(2)23(18(3)20-14-27(4,5)38-22(16)20)39(35,36)31-25(28)29-13-9-12-21(24(32)33)30-26(34)37-15-19-10-7-6-8-11-19;7-6-4-2-1-3-5-6/h6-8,10-11,21H,9,12-15H2,1-5H3,(H,30,34)(H,32,33)(H3,28,29,31);6H,1-5,7H2/t21-;/m0./s1
InChI Key
VDQHDVIYBBISOZ-BOXHHOBZSA-N
Canonical SMILES
CC1=C2C(=C(C(=C1C)S(=O)(=O)NC(=NCCCC(C(=O)O)NC(=O)OCC3=CC=CC=C3)N)C)CC(O2)(C)C.C1CCC(CC1)N

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