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Z-L-Asp(tBu)-ONp

Z-L-Asp(tBu)-ONp is a protected L-aspartic acid derivative featuring an aspartate side chain with a tert-butyl-protected carboxyl group and an N-benzyloxycarbonyl (Z/Cbz) protecting group on the amino functionality, with the α-carboxyl converted to an ONp ester. The molecule contains an ONp (p-nitrophenyl) ester at the carboxylate position, providing a leaving group-bearing activated ester while retaining the protected side-chain carboxyl as a tert-butyl ester, and the stereochemistry is specified as L by the product name. Z-L-Asp(tBu)-ONp is used as an activated amino acid building block for peptide synthesis and related coupling chemistry, where the ONp ester form supports carboxyl activation and can be employed in the preparation of aspartyl-containing peptide intermediates and aspartate derivatives for structure-activity and labeling studies.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25474

CAS No:17543-17-8

Synonyms/Alias:17543-17-8;(S)-4-tert-Butyl1-(4-nitrophenyl)2-(((benzyloxy)carbonyl)amino)succinate;AmbotzZAA1198;Z-L-Asp(tBu)-ONp;Z-ASP(OTBU)-ONP;CTK8B8725;MolPort-008-269-446;9189AA;ANW-61128;ZINC71788206;AKOS016003410;AK-60175;KB-288739;TC-149873;4-(2-Methyl-2-propanyl)1-(4-nitrophenyl)N-[(benzyloxy)carbonyl]-L-aspartate;N-[(Benzyloxy)carbonyl]-L-asparticacid4-tert-butyl1-(4-nitrophenyl)ester

Chemical Name:N-alpha-Benzyloxycarbonyl-L-aspartic acid alpha-p-nitrophenyl beta-t-butyl ester

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M.F/Formula
C22H24N2O8
M.W/Mr.
444,42 g/mole
Size
5 g;
InChI
1S/C22H24N2O8/c1-22(2,3)32-19(25)13-18(23-21(27)30-14-15-7-5-4-6-8-15)20(26)31-17-11-9-16(10-12-17)24(28)29/h4-12,18H,13-14H2,1-3H3,(H,23,27)/t18-/m0/s1
InChI Key
KAURUWJRWPNSJD-SFHVURJKSA-N
Canonical SMILES
CC(C)(C)OC(=O)CC(C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])NC(=O)OCC2=CC=CC=C2

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