Z-L-Asp(tBu)-ONp is a protected L-aspartic acid derivative featuring an aspartate side chain with a tert-butyl-protected carboxyl group and an N-benzyloxycarbonyl (Z/Cbz) protecting group on the amino functionality, with the α-carboxyl converted to an ONp ester. The molecule contains an ONp (p-nitrophenyl) ester at the carboxylate position, providing a leaving group-bearing activated ester while retaining the protected side-chain carboxyl as a tert-butyl ester, and the stereochemistry is specified as L by the product name. Z-L-Asp(tBu)-ONp is used as an activated amino acid building block for peptide synthesis and related coupling chemistry, where the ONp ester form supports carboxyl activation and can be employed in the preparation of aspartyl-containing peptide intermediates and aspartate derivatives for structure-activity and labeling studies.
CAT No: CP25474
CAS No:17543-17-8
Synonyms/Alias:17543-17-8;(S)-4-tert-Butyl1-(4-nitrophenyl)2-(((benzyloxy)carbonyl)amino)succinate;AmbotzZAA1198;Z-L-Asp(tBu)-ONp;Z-ASP(OTBU)-ONP;CTK8B8725;MolPort-008-269-446;9189AA;ANW-61128;ZINC71788206;AKOS016003410;AK-60175;KB-288739;TC-149873;4-(2-Methyl-2-propanyl)1-(4-nitrophenyl)N-[(benzyloxy)carbonyl]-L-aspartate;N-[(Benzyloxy)carbonyl]-L-asparticacid4-tert-butyl1-(4-nitrophenyl)ester
Chemical Name:N-alpha-Benzyloxycarbonyl-L-aspartic acid alpha-p-nitrophenyl beta-t-butyl ester
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