Z-L-aspartic acid β-methyl ester is an L-aspartic acid derivative in which the β-carboxyl group is esterified as a methyl ester and the α-amino group is protected by a benzyloxycarbonyl (Z, Cbz) group, giving a protected amino acid ester suitable for peptide-related chemistry. The molecule contains a Z-carbamate protecting group on nitrogen, an esterified β-carboxyl functionality, and a free α-carboxylic acid, with the aspartate side chain bearing a β-methyl-substituted carboxylate that modulates polarity and conformational preferences relative to unmodified aspartic acid. In synthesis, this protected amino acid ester functions as a substrate for constructing aspartate-containing peptide fragments in stepwise or solid-phase peptide assembly, where the orthogonal protection pattern helps control chemoselectivity during coupling and subsequent deprotection steps.
CAT No: CP00435
CAS No:3160-47-2
Synonyms/Alias:Z-Asp(OMe)-OH;3160-47-2;(S)-2-N-Cbz-amino-succinicacid4-methylester;Z-L-Asparticacid4-methylester;N-Benzyloxycarbonyl-L-asparticacid4-methylester;(S)-2-(((Benzyloxy)carbonyl)amino)-4-methoxy-4-oxobutanoicacid;N-Cbz-L-asparticacidbeta-methylester;Asparticacid,N-[(phenylmethoxy)carbonyl]-,4-methylester;PubChem14062;Z-ASP-OH;96002_ALDRICH;SCHEMBL3012469;96002_FLUKA;CTK8E6107;MolPort-002-500-067;ACT05245;ZINC2504640;Cbz-L-asparticacid4-methylester;CZ-030;SBB066265;AKOS010367422;AKOS015924117;RP29858;RTC-066713;AJ-36010
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