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Z-L-Lys(Z)-OSu

Z-L-Lys(Z)-OSu is a protected lysine derivative in which the α-amino group is carbobenzyloxy-protected (Z) and the ε-amino side chain is also protected as a Z carbamate, while the carboxyl group is converted to an N-hydroxysuccinimide (OSu) ester. The molecule therefore contains two protected amines that reduce undesired nucleophilicity during coupling chemistry, and it bears an activated OSu ester that can undergo acyl transfer to form amide bonds with appropriate nucleophiles under standard peptide-conjugation or labeling conditions. In synthetic and chemical biology workflows, this activated, doubly protected lysine analogue is used as a precursor for preparing lysine-containing amide linkages in peptide-related intermediates and bioconjugation targets where controlled installation of a lysine side chain is required.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25607

CAS No:2116-83-8

Synonyms/Alias:Z-Lys(Z)-OSu;2116-83-8;Nalpha,Nepsilon-Di-Z-L-lysinehydroxysuccinimideester;96885_ALDRICH;SCHEMBL9976419;96885_FLUKA;CTK8F0216;MolPort-003-939-971;C26H29N3O8;0802AB;ZINC71788228;AKOS015855377;AKOS015895737;AK-81332;KB-118725;TC-066819;FT-0658285;ST24050370;ST51053061;K-6094;N|A,N|A-Di-Z-L-lysinehydroxysuccinimideester;I06-1409

Chemical Name:N-alpha-N-epsilon-Bis-benzyloxycarbonyl-L-lysine succinimidyl ester

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M.F/Formula
C26H29N3O8
M.W/Mr.
511,51 g/mole
Size
5 g;25 g;
InChI
1S/C26H29N3O8/c30-22-14-15-23(31)29(22)37-24(32)21(28-26(34)36-18-20-11-5-2-6-12-20)13-7-8-16-27-25(33)35-17-19-9-3-1-4-10-19/h1-6,9-12,21H,7-8,13-18H2,(H,27,33)(H,28,34)/t21-/m0/s1
InChI Key
LHOAUCZIIQFZMI-NRFANRHFSA-N
Canonical SMILES
C1CC(=O)N(C1=O)OC(=O)C(CCCCNC(=O)OCC2=CC=CC=C2)NC(=O)OCC3=CC=CC=C3

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