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Z-L-Nle-ONp

Z-L-Nle-ONp is a protected amino acid derivative in which the amino acid is the L-form of norleucine (Nle) bearing a benzyloxycarbonyl (Z, Cbz) protecting group on the α-amino functionality and an ONp ester (p-nitrophenyl ester) at the carboxyl group. The molecule therefore contains a carbamate-protected amine and an activated carboxylate ester, with the side chain featuring a straight-chain aliphatic functionality typical of norleucine and a stereocenter consistent with the L designation. Z-L-Nle-ONp is commonly used as a building block for peptide coupling and as a substrate-like activated amino acid derivative in synthetic workflows where the p-nitrophenyl ester can serve as a leaving-group-bearing carboxyl activation handle, including preparation of peptide-related intermediates and derivatized amide products.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP25650

CAS No:24181-97-3

Synonyms/Alias:24181-97-3;Z-NLE-ONP;Z-D-2-Aminohexanoicacid4-nitrophenylester

Chemical Name:N-alpha-Benzyloxycarbonyl-L-norleucine p-nitrophenyl ester

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cGMP Peptide
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M.F/Formula
C12H16N2O4
M.W/Mr.
386,39 g/mole
Size
5 g;25 g;
InChI
1S/C12H16N2O4/c1-2-3-4-11(13)12(15)18-10-7-5-9(6-8-10)14(16)17/h5-8,11H,2-4,13H2,1H3
InChI Key
ZCYAXSMOAFDRPQ-UHFFFAOYSA-N
Canonical SMILES
CCCCC(C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])N

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