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Z-L-Phenylalanine amide

Z-L-Phenylalanine amide is a protected amino acid amide derivative in which the amino acid framework is converted to the corresponding carboxamide and the α-amino group is protected with a benzyloxycarbonyl (Cbz, "Z") group, while the side chain remains the benzyl-bearing phenylalanine moiety. The molecule therefore contains a Cbz-protected nitrogen (carbamate), a free amide carbonyl as the carboxyl functional group, and the aromatic side chain characteristic of phenylalanine, with stereochemistry specified as L at the α-carbon. In peptide-related synthesis and chemical biology workflows, this protected amino acid amide functions as a defined building block for preparing peptide amides or for studying amide-containing analogues where controlled N-protection and an amide terminus are required for chemoselective coupling and downstream deprotection steps.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01624

CAS No:4801-80-3

Synonyms/Alias:4801-80-3;(S)-Benzyl(1-amino-1-oxo-3-phenylpropan-2-yl)carbamate;Z-PHE-NH2;ZINC00218234;AmbotzZAA1235;Z-L-Phenylalanineamide;AC1MBSD7;SCHEMBL764062;CHEMBL2042018;HHBOFAIEPRHUSR-HNNXBMFYSA-N;MolPort-002-494-158;ZINC218234;AKOS004910430;AM82178;AJ-18009;AK117101;ZB009563;N-Alpha-Carbobenzoxy-L-phenylalanineamide;ST2414653;K-9160;Nalpha-[(Phenylmethoxy)carbonyl]-L-phenylalaninamide;benzylN-[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]carbamate

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M.F/Formula
C17H18N2O3
M.W/Mr.
298.3
Abbr
Z-Phe-NH2
InChI
1S/C17H18N2O3/c18-16(20)15(11-13-7-3-1-4-8-13)19-17(21)22-12-14-9-5-2-6-10-14/h1-10,15H,11-12H2,(H2,18,20)(H,19,21)/t15-/m0/s1
InChI Key
HHBOFAIEPRHUSR-HNNXBMFYSA-N
Canonical SMILES
C1=CC=C(C=C1)CC(C(=O)N)NC(=O)OCC2=CC=CC=C2

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