Z-L-Proline amide

Z-L-Proline amide contains an L-proline backbone in which the carboxyl group is converted to an amide, retaining the five-membered pyrrolidine ring as the defining amino acid side chain. The molecule bears a Z (benzyloxycarbonyl) protecting group on the amino functionality, and it presents an amide carbonyl alongside the protected nitrogen, with stereochemistry indicated as L for the proline center. Z-L-Proline amide is used as a protected amino acid amide building block for preparing peptide-related intermediates and for controlled incorporation of proline-derived motifs in solution-phase or solid-phase peptide synthesis workflows, where chemoselectivity around the amide and protected amine is required.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01715

CAS No:34079-31-7

Synonyms/Alias:34079-31-7;z-pro-nh2;cbz-l-prolinamide;(s)-benzyl2-carbamoylpyrrolidine-1-carboxylate;cbz-pro-nh2;(S)-1-N-Cbz-prolinamide;Z-L-Prolinamide;z-l-prolineamide;Carbobenzyloxy-L-prolinamide;n-carbobenzoxy-l-prolineamide;Benzyloxycarbonyl-L-prolinamide;(s)-2-carbamoyl-1-cbz-pyrrolidine;N-CARBOBENZOXY-L-PROLINAMIDE;BENZYLOXYCARBONYL-L-PROLINEAMIDE;N-BENZYLOXYCARBONYL-L-PROLINAMIDE;benzyl(2S)-2-carbamoylpyrrolidine-1-carboxylate;(R)-2-carbamoyl-n-cbz-pyrrolidine;cbz-l-pronh;z-pro-nh;n-cbz-l-prolinamide;ZINC00399373;PubChem5690;AC1OCUSW;PubChem19024;(S)-N-Cbz-Prolinamide

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M.F/Formula
C13H16N2O3
M.W/Mr.
248.3
Abbr
Z-Pro-NH2
InChI
1S/C13H16N2O3/c14-12(16)11-7-4-8-15(11)13(17)18-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H2,14,16)/t11-/m0/s1
InChI Key
ZCGHEBMEQXMRQL-NSHDSACASA-N
Canonical SMILES
C1CC(N(C1)C(=O)OCC2=CC=CC=C2)C(=O)N

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