Z-Lys(Boc)-ONp contains a lysine α-amino acid framework bearing an Nα-protecting benzyloxycarbonyl (Z) group and a Boc-protected side-chain amino (Lys(Boc)), with the carboxyl functionality converted to an ONp ester (ONp = p-nitrophenyl ester). The molecule therefore presents a protected α-amino acid moiety, a Boc-protected ε-amino group, and an activated carboxyl ester that can undergo nucleophilic acyl substitution under appropriate conditions while the Z and Boc groups help control chemoselectivity by masking the amines. Z-Lys(Boc)-ONp is used as a protected, activated amino acid derivative and acylating intermediate in peptide synthesis workflows and in solution-phase or solid-phase assembly strategies where stepwise coupling of the protected lysine residue is required.
CAT No: CP26815
CAS No:2212-69-3
Synonyms/Alias:Z-Lys(Boc)-ONp;2212-69-3;(S)-4-Nitrophenyl2-(((benzyloxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoate;SCHEMBL7302025;CTK8E9760;MolPort-003-939-914;1216AB;ZINC71788211;AKOS015841480;AKOS016002115;AK-49576;AB0089596;KB-118005;TC-066815;ST24036192;Z-N-Epsilon-boc-L-lysine4-nitrophenylester;J-300185;Q-101588
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