Z-Lys(isopropyl)-OH contains the amino acid framework of lysine bearing an isopropyl-substituted side-chain, with the α-amino and α-carboxyl functional groups present as a free amino acid derivative. The α-amino group is protected by a benzyloxycarbonyl (Z, Cbz) protecting group, while the side-chain modification introduces a branched hydrophobic isopropyl substituent that changes steric and nonpolar character relative to unmodified lysine. Z-Lys(isopropyl)-OH is used as a protected, side-chain-modified lysine building block for peptide synthesis and for structure-activity or chemical biology studies that require incorporation of a hydrophobic lysine analogue into peptide-related intermediates.
CAT No: CP26799
CAS No:218938-55-7
Synonyms/Alias:Z-Nepsilon-isopropyl-L-Lysine;218938-55-7;Z-LYS(ISOPROPYL)-OH;CTK8E7251;ZINC2244309;AKOS025294922;RT-016318;L-Lysine,N6-(1-methylethyl)-N2-[(phenylmethoxy)carbonyl]-
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