Z-N-Me-Phe-OH is a protected, N-methylated phenylalanine derivative in which the amino group is carbobenzyloxy-protected (Z, benzyloxycarbonyl) and the α-carboxylic acid remains unesterified. The molecule contains a free carboxylic acid functional group and a side-chain benzyl group characteristic of phenylalanine, while the nitrogen bears an additional methyl substituent that changes its steric and electronic properties relative to the corresponding unmodified amino acid. Z-N-Me-Phe-OH is used as a building block for peptide-related synthesis and for preparing more complex amino acid and peptide derivatives where controlled chemoselectivity and an N-methylated backbone are required for structure-activity studies or chemical labeling workflows.
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