Z-O-tert.butyl-D-serine

Z-O-tert.butyl-D-serine is a protected serine derivative in which the amino acid side chain bears a tert-butyl ether (O-tert-butyl) and the amino group is protected as a benzyloxycarbonyl-type carbamate (Z). The molecule contains a carboxylic acid functionality and a stereogenic center corresponding to D-serine, with the serine side chain hydroxyl masked as an ether to control chemoselectivity during peptide coupling and subsequent deprotection. Z-O-tert.butyl-D-serine is used as a stepwise building block for peptide synthesis and as a protected intermediate for preparing serine-containing peptide analogues or other serine-derived conjugates where selective handling of the side-chain oxygen is required.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01831

CAS No:65806-90-8

Synonyms/Alias:z-d-ser(tbu)-oh;65806-90-8;Cbz-O-tert-butyl-D-serine;(R)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoicacid;AmbotzZAA1152;AC1LW0DX;AC1Q1NGU;SCHEMBL607263;N-CBz-O-tert-butyl-D-serine;CTK8B9885;MolPort-006-701-063;ACT10885;ZINC2049224;ANW-63421;CZ-126;FC0807;KM0956;AKOS015910119;AJ-33456;AK-81320;AB0007173;RT-002585;FT-0686538;N-Alpha-Carbobenzoxy-D-serineT-butylether;ST24035216

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M.F/Formula

C15H21NO5

M.W/Mr.

295.3

Abbr

Z-D-Ser(tBu)-OH

InChI

1S/C15H21NO5/c1-15(2,3)21-10-12(13(17)18)16-14(19)20-9-11-7-5-4-6-8-11/h4-8,12H,9-10H2,1-3H3,(H,16,19)(H,17,18)/t12-/m1/s1

InChI Key

TXDGEONUWGOCJG-GFCCVEGCSA-N

Canonical SMILES

CC(C)(C)OCC(C(=O)O)NC(=O)OCC1=CC=CC=C1

1. Urinary Metabolites Associated with Blood Pressure on a Low-or High-Sodium Die

2. The effect of sex on immune responses to a homocitrullinated peptide in the DR4-transgenic mouse model of Rheumatoid Arthritis

3. Identification, Localization in the Central Nervous System and Novel Myostimulatory Effect of Allatostatins in Tenebrio molitor Beetle

4. Glucagonlike peptide 2 analogue teduglutide: stimulation of proliferation but reduction of differentiation in human Caco-2 intestinal epithelial cells

5. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs

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