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Z-O-tert.butyl-L-serine methyl ester

Z-O-tert.butyl-L-serine methyl ester contains an L-serine-derived amino acid framework in which the side-chain hydroxymethyl group is O-tert-butyl protected and the amino acid carboxyl group is present as a methyl ester. The molecule bears a benzyloxycarbonyl (Z) protecting group on the amino functionality, yielding a carbamate that masks the α-amino group while maintaining the serine backbone, and the stereochemistry is specified as L by the product name. This protected amino acid ester is used as a stepwise building block for peptide synthesis and related derivative preparation, where the combination of N-protection and side-chain O-protection supports controlled chemoselectivity during coupling and subsequent deprotection to reveal the serine hydroxyl for further functionalization.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP01833

CAS No:1872-59-9

Synonyms/Alias:1872-59-9;(S)-Methyl2-(((benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanoate;CTK8B9848;MolPort-023-331-653;ZINC2556681;ANW-63300;Z-O-tert.butyl-L-serinemethylester;AKOS015911690;AM82235;AJ-39946;AK-87738;TR-008659;ST24036301;I14-37406

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M.F/Formula
C16H23NO5
M.W/Mr.
309.4
Abbr
Z-Ser(tBu)-OMe
InChI
1S/C16H23NO5/c1-16(2,3)22-11-13(14(18)20-4)17-15(19)21-10-12-8-6-5-7-9-12/h5-9,13H,10-11H2,1-4H3,(H,17,19)/t13-/m0/s1
InChI Key
UMAXPCYVVRYQNO-ZDUSSCGKSA-N
Canonical SMILES
CC(C)(C)OCC(C(=O)OC)NC(=O)OCC1=CC=CC=C1

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