5-FAM-PMDM6 (PMDM6-F)

    PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.

    Please kindly note that our products and services can only be used to support research purposes (Not for clinical use).

    CAT No: X21168

    Quick InquiryCustom Peptide Synthesis

    cGMP Peptide

    Registration of APIs CMC information required for an IND

    IND and NDA support Drug master files (DMF) filing

    Specification Technical Data Publications Customer reviews and Q&A
    Synonyms/Alias5-FAM-PMDM6; HY-P5367; CS-0884888
    M.W/Mr.1784.3
    SequenceOne Letter Code: 5-FAM-(β-A)-(β-A)-FM-Aib-pY-(6-Cl-DL-Trp)-E-Ac3c-LN-NH2
    Three Letter Code: 5-FAM-β-Ala-β-Ala-Phe-Met-*Aib-pTyr-(*6-Cl-DL-Trp)-Glu-*Ac3c-Leu-Asn-NH2(*Aib:α-aminoisobutyric acid;*6-CI-DL-Trp:6-chloro-DL-tryptoptophan;*Ac3c:1-amino-cyclopropanecarboxylic acid)
    InChIInChI=1S/C84H96ClN14O24PS/c1-43(2)33-61(73(109)94-60(71(87)107)41-67(86)102)97-81(117)83(28-29-83)99-78(114)57(23-24-70(105)106)92-76(112)64(37-47-42-90-59-38-48(85)14-19-52(47)59)95-75(111)63(35-45-11-17-51(18-12-45)123-124(118,119)120)96-80(116)82(3,4)98-77(113)58(27-32-125-5)93-74(110)62(34-44-9-7-6-8-10-44)91-69(104)26-30-88-68(103)25-31-89-72(108)46-13-20-54-53(36-46)79(115)122-84(54)55-21-15-49(100)39-65(55)121-66-40-50(101)16-22-56(66)84/h6-22,36,38-40,42-43,57-58,60-64,90,100-101H,23-35,37,41H2,1-5H3,(H2,86,102)(H2,87,107)(H,88,103)(H,89,108)(H,91,104)(H,92,112)(H,93,110)(H,94,109)(H,95,111)(H,96,116)(H,97,117)(H,98,113)(H,99,114)(H,105,106)(H2,118,119,120)/t57-,58-,60-,61-,62-,63-,64-/m0/s1
    InChI KeySOJWFPRRLDTYFP-XYVYTFQOSA-N
    ReferencesDing, K. et al. J Med Chem 49, 3432 (2006).

    1. Cationic cell-penetrating peptides are potent furin inhibitors

    2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs

    3. GLP-1, exendin-4 and C-peptide regulate pancreatic islet microcirculation, insulin secretion and glucose tolerance in rats

    4. Investigating Potential Interactions Between Neurohypophyseal Peptides, their Drug Analogs, and Coagulation Factor VIII

    5. Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

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