Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1, caspases-4, caspases-5, and caspases-11 , but not the apoptotic caspases such as caspase-3.
CAT# | OPO-005 |
CAS | 2376255-48-8 |
Synonyms/Alias | N-acetyl-Phe-Leu-Thr-Asp-chloromethylketone, GSDMD-derived inhibitor |
Chemical Name | (3S)-3-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-chloro-4-oxopentanoic acid |
M.F/Formula | C26H37ClN4O8 |
M.W/Mr. | 569.05 |
Sequence | N-acetyl-Phe-Leu-Thr-Asp-chloromethylketone |
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