Ac-FLTD-CMK, a gasdermin D (GSDMD)-derived inhibitor, is a specific inflammatory caspases inhibitor. Ac-FLTD-CMK is effective against caspases-1, caspases-4, caspases-5, and caspases-11 , but not the apoptotic caspases such as caspase-3.
CAT No: OPO-005
CAS No:2376255-48-8
Synonyms/Alias:Ac-FLTD-CMK;2376255-48-8;(3S)-3-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-chloro-4-oxopentanoic acid;(4S,7S,10S,13S)-4-Benzyl-13-(2-chloroacetyl)-10-((R)-1-hydroxyethyl)-7-isobutyl-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid;starbld0009421;Ac-FLTD-CMK?;AKOS040755475;AT34795;DA-60736;MS-30287;HY-111675;CS-0089824;
Chemical Name:(3S)-3-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-acetamido-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxybutanoyl]amino]-5-chloro-4-oxopentanoic acid
1. Emu oil in combination with other active ingredients for treating skin imperfections
2. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
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