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Ac-Leu-Glu-His-Asp-AFC

Ac-Leu-Glu-His-Asp-AFC is a fluorogenic substrate featuring an AFC reporter for monitoring proteolytic activity. Its acidic and aromatic residues support specific substrate recognition. The peptide is widely used for kinetic and mechanistic studies. Applications include enzymology, catalytic profiling, and substrate-specificity screening.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Ac-Leu-Glu-His-Asp-AFC(CAS 210345-03-2)

CAT No: C11101

CAS No:210345-03-2

Synonyms/Alias:Ac-LEHD-AFC;210345-03-2;(4S)-4-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid;LEHD;Ac-LEHD-AFC? (trifluoroacetate salt);MFCD01862610;SCHEMBL4468806;HY-P1093;AKOS024456676;CS-0027699;N-Acetyl-Leu-Glu-His-Asp-7-amino-4-(trifluoromethyl)coumarin;N-Acetyl-Leu-Glu-His-Asp-7-amido-4-trifluoromethylcoumarin, >=95% (HPLC), powder;

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M.F/Formula
C33H38F3N7O11
M.W/Mr.
765.7
Sequence
One Letter Code:LEHD
InChI
InChI=1S/C33H38F3N7O11/c1-15(2)8-22(39-16(3)44)31(52)41-21(6-7-26(45)46)29(50)42-23(9-18-13-37-14-38-18)32(53)43-24(12-27(47)48)30(51)40-17-4-5-19-20(33(34,35)36)11-28(49)54-25(19)10-17/h4-5,10-11,13-15,21-24H,6-9,12H2,1-3H3,(H,37,38)(H,39,44)(H,40,51)(H,41,52)(H,42,50)(H,43,53)(H,45,46)(H,47,48)/t21-,22-,23-,24-/m0/s1
InChI Key
HULKIXRFKRCRHD-ZJZGAYNASA-N

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