Ac-N-Me-Tyr-Val-Ala-Asp-aldehyde (pseudo acid) acts as a peptide aldehyde known for forming reversible complexes with catalytic residues. The N-methylated tyrosine enhances hydrophobic packing and influences conformational preferences. Its aldehyde functionality enables mechanistic studies on proteolytic inhibition and transition-state mimicry. Researchers utilize it in enzymology, structural studies, and peptide-based inhibitor design.
1. SERS spectrum of the peptide thymosin‐β4 obtained with Ag nanorod substrate
2. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
3. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
4. TMEM16F and dynamins control expansive plasma membrane reservoirs
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