Acetyl-(Ala10.11)-RANTES (1-14) amide (human) is a chemokine-derived fragment featuring dual alanine substitutions that refine local steric interactions. The N-terminal acetylation enhances stability and modulates charge distribution. Its shortened sequence enables focused mapping of RANTES receptor-binding determinants. Researchers use it to analyze structure-activity features of CC-chemokine recognition.
1. Autoinhibition and phosphorylation-induced activation of phospholipase C-γ isozymes
4. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
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