Acetyl Hexapeptide-49 is a synthetic peptide designed for use in cosmetic formulations targeting sensitive or reactive skin. It supports skin comfort by helping to maintain the skin's natural barrier function and promoting a balanced appearance. Suitable for a range of leave-on products, Acetyl Hexapeptide-49 can be incorporated into emulsions, serums, and gels, aligning with regulatory requirements for global cosmetic applications.
CAT No: CPC1670
Mechanism of Action (MOA)
Acetyl Hexapeptide-49 is a synthetic signal peptide designed to interact with skin cell receptors involved in the modulation of neurogenic communication pathways. By mimicking a specific sequence within natural skin peptides, it is suggested to influence the release of signaling molecules from sensory nerve endings. This action may help support the skin's response to external stimuli by modulating cellular communication processes associated with skin comfort and barrier function.
Acetyl Hexapeptide-49 is suitable for incorporation into a variety of topical cosmetic formulations.
- Facial serums for daily skincare routines- Lightweight emulsions such as lotions and creams- Sheet masks and leave-on gel masks- Eye contour products- After-sun or post-procedure soothing products- Formulations designed for sensitive skin types
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Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.