ACTH alpha (1-18)

ACTH alpha (1-18) is an N-terminal peptide containing aromatic and charged residues central to structural transitions in ACTH-derived sequences. Its amphipathic profile supports receptor-interaction studies. The sequence enables mapping of early motif determinants. Researchers apply it in biochemical analysis of melanocortin peptides.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
ACTH alpha (1-18)(CAS 1285-85-4)

CAT No: A03053

CAS No:1285-85-4

Synonyms/Alias:ACTH alpha (1-18);alpha 1-18 Acth;ACTH alpha(1-18);1-18 Acth;Acth a(1-18);1285-85-4;alpha1-18-Corticotropin;DTXSID10155914;DTXCID0078405;

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cGMP Peptide
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  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C101H157N33O24S
M.W/Mr.
2249.6
Sequence
One Letter Code:SYSMEHFRWGKPVGKKRR
Three Letter Code:H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-OH
InChI
InChI=1S/C101H157N33O24S/c1-56(2)82(96(155)118-52-79(138)120-65(23-9-12-37-102)85(144)122-66(24-10-13-38-103)86(145)123-67(26-15-40-113-99(106)107)87(146)127-72(98(157)158)28-17-42-115-101(110)111)133-95(154)78-29-18-43-134(78)97(156)71(25-11-14-39-104)121-80(139)51-117-84(143)75(47-59-49-116-64-22-8-7-21-62(59)64)130-88(147)68(27-16-41-114-100(108)109)124-91(150)74(45-57-19-5-4-6-20-57)129-93(152)76(48-60-50-112-55-119-60)131-89(148)69(34-35-81(140)141)125-90(149)70(36-44-159-3)126-94(153)77(54-136)132-92(151)73(128-83(142)63(105)53-135)46-58-30-32-61(137)33-31-58/h4-8,19-22,30-33,49-50,55-56,63,65-78,82,116,135-137H,9-18,23-29,34-48,51-54,102-105H2,1-3H3,(H,112,119)(H,117,143)(H,118,155)(H,120,138)(H,121,139)(H,122,144)(H,123,145)(H,124,150)(H,125,149)(H,126,153)(H,127,146)(H,128,142)(H,129,152)(H,130,147)(H,131,148)(H,132,151)(H,133,154)(H,140,141)(H,157,158)(H4,106,107,113)(H4,108,109,114)(H4,110,111,115)/t63-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,76-,77-,78-,82-/m0/s1
InChI Key
UKJCLEMFCYKKPS-FKOMBOBKSA-N

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