Bio-11006 is a peptide-derived construct enriched in hydrophobic, polar, and aromatic residues that promote structural adaptability. Researchers use it to explore ligand-recognition principles, peptide-protein contacts, and solvent-sensitive folding. Its balanced sequence facilitates detailed conformational study. The motif is suited for advanced biophysical assays.
CAT No: R2290
CAS No:901117-03-1
Synonyms/Alias:BIO-11006;901117-03-1;AC-GAQFSKTAAK;(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-acetamidoacetyl)amino]propanoyl]amino]-5-amino-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-hydroxypropanoyl]amino]-6-aminohexanoyl]amino]-3-hydroxybutanoyl]amino]propanoyl]amino]propanoyl]amino]-6-aminohexanoic acid;L-LYSINE, N-ACETYLGLYCYL-L-ALANYL-L-GLUTAMINYL-L-THREONYL-L-SERYL-L-LYSYL-L-THREONYL-L-ALANYL-L-ALANYL-;N-ACETYLGLYCYL-L-ALANYL-L-GLUTAMINYL-L-THREONYL-L-SERYL-L-LYSYL-L-THREONYL-L-ALANYL-L-ALANYL-L-LYSINE;BIO-11006 peptide;(2S)-2-(((2S)-2-(((2S)-2-(((2S,3R)-2-(((2S)-2-(((2S)-2-(((2S)-2-(((2S)-2-(((2S)-2-((2-acetamidoacetyl)amino)propanoyl)amino)-5-amino-5-oxopentanoyl)amino)-3-phenylpropanoyl)amino)-3-hydroxypropanoyl)amino)-6-aminohexanoyl)amino)-3-hydroxybutanoyl)amino)propanoyl)amino)propanoyl)amino)-6-aminohexanoic acid;Aerosolized BIO-11006;UNII-609AWV0US2;609AWV0US2;BIO11006;DB14886;MARCKS Protein Inhibitor BIO-11006;Myristoylated Alanine Rich C Kinase Substrate Inhibitor BIO-11006;
Bio-11006 is a synthetic peptide compound designed for advanced biochemical research applications, particularly within the fields of cellular signaling and neurobiology. As a sequence-defined peptide, it serves as a valuable tool for investigating protein-protein interactions, receptor modulation, and intracellular communication pathways. Its structure and functional motifs are tailored to mimic or disrupt specific biological processes, making it a versatile reagent for exploring mechanisms of action at the molecular level. The compound's utility extends to both in vitro and in vivo experimental settings, supporting a wide range of investigative and methodological approaches in modern life sciences.
Peptide signaling pathway studies: Bio-11006 is frequently employed in studies aimed at elucidating the intricacies of peptide-mediated signaling pathways. Researchers utilize it to probe the downstream effects of receptor activation or inhibition, enabling precise mapping of signaling cascades that govern cellular responses. Its defined sequence allows for targeted interaction with specific receptors or signaling proteins, facilitating the dissection of molecular events involved in processes such as synaptic transmission, hormone action, or immune modulation.
Protein interaction assays: The compound is a valuable reagent in assays designed to characterize protein-protein interactions. By serving as either a ligand or competitive inhibitor, Bio-11006 enables the investigation of binding affinities, conformational changes, and interaction specificity within complex biological systems. These studies are critical for understanding the molecular underpinnings of cellular communication and for identifying novel regulatory mechanisms that may be leveraged in future research.
Functional peptide analysis: In peptide structure-function studies, Bio-11006 provides a robust platform for evaluating the biological activity of specific amino acid motifs. Researchers employ the compound to assess the impact of sequence modifications on function, stability, and cellular uptake, thereby gaining insights into the determinants of peptide efficacy. Such analyses are essential for advancing peptide engineering, optimizing molecular design, and developing next-generation research tools.
Cellular model development: The peptide is also utilized in the development and refinement of cellular models for experimental research. By introducing Bio-11006 into cultured cells, investigators can modulate signaling networks, induce specific phenotypic changes, or create defined experimental conditions for downstream analyses. Its application in model systems supports the validation of biological hypotheses and the exploration of cellular responses under controlled perturbations.
Analytical method calibration: In addition to its direct experimental uses, Bio-11006 serves as a reference or calibration standard for various analytical techniques, including mass spectrometry and chromatographic separation of peptides. Its well-characterized properties enable accurate quantification, method validation, and performance benchmarking, ensuring reliability and reproducibility in peptide analysis workflows. This application is particularly valuable for laboratories seeking to standardize measurements and maintain high analytical rigor in peptide research.
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