C5a Receptor Agonist, mouse, human
C5a Receptor Agonist, mouse, human
This peptide is derived from the C-terminus of the chemokine, complement fragment 5 anaphylatoxin (C5a). This peptide functions as a C5a receptor agonist. C5a is a plasma protein involved in cellular inflammatory processes by inducing chemotaxis, degranulation of leukocytes, increased vascular permeability, and cytokine production. The cyclohexylalanine at position 5 is crucial to agonist function. Arg at the last position is of the d-isomer.
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| CAT# | A19007 |
| M.W/Mr. | 853.1 |
| Sequence | One Letter Code: FKP-(D-Cha)-Cha-r
Three Letter Code: H-Phe-Lys-Pro-D-Cha-Cha-D-Arg-OH |
| Storage | -20°C |
References | Buck, E. et al. PNAS 102, 2719 (2005); Higginbottom, A. J Biol Chem 280, 17831 (2005). |
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