Cyclo(D-Ser-Pro-D-Val-Leu-D-Trp) contains alternating D-amino acids that impose a rigid macrocyclic topology. Its hydrophobic and polar residues create defined interaction surfaces. The cyclic structure supports studies of conformational constraints and receptor recognition. Applications include biophysical modeling, ligand design, and peptide engineering.
2. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
3. Implications of ligand-receptor binding kinetics on GLP-1R signalling
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