(Cyclo(Glu22-Lys26),Leu27)-pTH (1-31) amide (human) is a cyclized analog of parathyroid hormone (PTH), where the loop structure between Glu22 and Lys26 stabilizes the peptide's conformation and receptor interaction. The Leu27 substitution further enhances binding affinity. This modification supports high-resolution studies of PTH receptor binding and signaling dynamics in bone metabolism.
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