Cyclosporin A-Derivative 2 is a novel derivative from cyclosporin A. Cyclosporin A is an immunosuppressive agent which can bind to the cyclophilin and inhibit calcineurin.
Registration of APIs CMC information required for an IND
IND and NDA support Drug master files (DMF) filing
M.F/Formula | C₅₈H₁₀₄N₁₀O₁₃ |
M.W/Mr. | 1149.51 |
Sequence | One Letter Code: VLADALLV-Aaa-Abu-Sar three Letter Code: Val-Leu-Ala-D-Ala-Leu-Leu-Val-Aaa-Abu-Sar |
2. Store-operated Ca2+ entry sustains the fertilization Ca2+ signal in pig eggs
4. Emu oil in combination with other active ingredients for treating skin imperfections
5. TMEM16F and dynamins control expansive plasma membrane reservoirs
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