This peptide corresponds to the protein transduction domain of the TAT protein and is synthesized with an activated cysteine residue C(Npys), wherein Npys is 3-Nitro-2-pyridinesulfenyl group and is used for activating S of cysteine and for rapid reaction when a thiol group is introduced. This kind of modification has been used to render this peptide as a cell penetrating and carrier peptide applicable in conjugation studies.
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M.W/Mr. | 1816.1 |
Sequence | Cys(Npys)-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-NH2 |
Long-term Storage Conditions | Soluble in water for a solution up to 3 mg/ml, otherwise acetonitrile is recommend. Avoid repeated freezing and thawing. |
1. Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function
4. C-Peptide replacement therapy and sensory nerve function in type 1 diabetic neuropathy
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