(D-Ala2,N-Me-Phe4,glycinol5)-Enkephalin is a modified enkephalin analog featuring a D-alanine substitution at position 2 and a N-methylphenylalanine at position 4. These changes enhance stability and reduce susceptibility to enzymatic degradation, while the glycinol modification at position 5 alters receptor binding dynamics. Researchers use it to study opioid receptor subtypes and to probe the structure-activity relationship of enkephalin-like peptides.
1. Emu oil in combination with other active ingredients for treating skin imperfections
3. Immune-awakening Saccharomyces-inspired nanocarrier for oral target delivery to lymph and tumors
5. Peptides as Active Ingredients: A Challenge for Cosmeceutical Industry
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