Dodecanedioic acid informally referred to as DDDA is a saturated aliphatic dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitor, surfactant, and plastics. Experimental work with Dodecanedioic acid in type 2 diabetic patients has demonstrated that IV infusion helps to maintain normal blood sugar and energy levels without increasing the blood glucose load in the process.
CAT No: R1938
CAS No:693-23-2
Synonyms/Alias:1,12-Dodecanedioic acid; 1,10-Decanedicarboxylic acid; Decamethylenedicarboxylic acid
Dodecanedioic acid is a long-chain aliphatic dicarboxylic acid, recognized for its versatile chemical properties and importance in both biochemical research and industrial chemistry. As a saturated twelve-carbon diacid, it serves as a valuable building block for the synthesis of polymers, specialty chemicals, and functionalized materials. Its structural features render it highly relevant in studies involving lipid metabolism, enzyme specificity, and the development of bio-based materials. Dodecanedioic acid's unique combination of hydrophobicity and bifunctionality makes it an ideal substrate or intermediate in a variety of experimental and manufacturing contexts.
Polymer synthesis: Dodecanedioic acid is widely employed in the production of specialty polyamides and polyesters, where its dicarboxylic functionality enables the formation of high-performance polymers. Researchers and industrial chemists utilize it to create materials with enhanced mechanical strength, thermal stability, and chemical resistance. Its incorporation into polymer backbones is particularly valuable for engineering plastics, fibers, and resins, supporting innovation in sectors such as automotive, electronics, and textiles.
Metabolic studies: The compound serves as a model substrate for investigating fatty acid oxidation and dicarboxylic acid metabolism in biological systems. Its metabolic fate provides insight into peroxisomal and mitochondrial β-oxidation pathways, making it a useful tool for elucidating the enzymatic mechanisms governing lipid catabolism. By analyzing how cells process dodecanedioic acid, researchers can better understand disorders of fatty acid metabolism and the physiological roles of dicarboxylic acids.
Biochemical assay development: Due to its well-defined structure and reactivity, dodecanedioic acid is used in the development and calibration of analytical assays targeting dicarboxylic acids. It acts as a standard or reference compound in chromatographic and spectrometric techniques, facilitating the quantification and identification of related metabolites in complex biological samples. This application is essential for advancing lipidomics and metabolic profiling studies.
Surface modification and materials science: The bifunctional nature of dodecanedioic acid allows it to act as a linker or crosslinking agent in the functionalization of surfaces and nanoparticles. Its ability to form stable covalent bonds with various substrates is harnessed to tailor surface properties, improve biocompatibility, or introduce reactive groups for further derivatization. These modifications are crucial in the design of advanced coatings, biomedical devices, and nanomaterials.
Chemical synthesis intermediate: Owing to its chain length and dual carboxylic acid groups, dodecanedioic acid is frequently used as a precursor in the synthesis of esters, amides, and other derivatives. Synthetic chemists exploit its reactivity to generate novel compounds for research, including surfactants, lubricants, and specialty monomers. The compound's versatility as a synthetic intermediate underpins its value in both exploratory research and applied chemical manufacturing.
If you have any peptide synthesis requirement in mind, please do not hesitate to contact us at . We will endeavor to provide highly satisfying products and services.
Creative Peptides is a trusted CDMO partner specializing in high-quality peptide synthesis, conjugation, and manufacturing under strict cGMP compliance. With advanced technology platforms and a team of experienced scientists, we deliver tailored peptide solutions to support drug discovery, clinical development, and cosmetic innovation worldwide.
From custom peptide synthesis to complex peptide-drug conjugates, we provide flexible, end-to-end services designed to accelerate timelines and ensure regulatory excellence. Our commitment to quality, reliability, and innovation has made us a preferred partner across the pharmaceutical, biotechnology, and personal care industries.
Read More