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Dodecanedioic acid

Dodecanedioic acid informally referred to as DDDA is a saturated aliphatic dicarboxylic acid mainly used in antiseptics, top-grade coatings, painting materials, corrosion inhibitor, surfactant, and plastics. Experimental work with Dodecanedioic acid in type 2 diabetic patients has demonstrated that IV infusion helps to maintain normal blood sugar and energy levels without increasing the blood glucose load in the process.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.
Dodecanedioic acid(CAS 693-23-2)

CAT No: R1938

CAS No:693-23-2

Synonyms/Alias:1,12-Dodecanedioic acid; 1,10-Decanedicarboxylic acid; Decamethylenedicarboxylic acid

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M.F/Formula
C12H22O4
M.W/Mr.
230.3
Appearance
Solid
Biological Activity
Dodecanedioic acid is an alpha,omega-dicarboxylic acid that is dodecane in which the methyl groups have been oxidised to the corresponding carboxylic acids. It has a role as an EC 1.1.1.1 (alcohol dehydrogenase) inhibitor and a human metabolite. It is a conjugate acid of a dodecanedioate(2-). It derives from a hydride of a dodecane.
Long-term Storage Conditions
Soluble in ethanol (0.1 g/L) at 20° C, hot methanol, and water (0.04 g/L) at 20° C.
InChI
InChI=1S/C12H22O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h1-10H2,(H,13,14)(H,15,16)
InChI Key
TVIDDXQYHWJXFK-UHFFFAOYSA-N
Canonical SMILES
C(CCCCCC(=O)O)CCCCC(=O)O
References
1. Mingrone, G. et al. 1996. JPEN J Parenter Enteral Nutr. 20(1): 38-42. PMID: 8788261
2. Bertuzzi, A. et al. 1997. Br. J. Nutr. 78(1): 143-153. PMID: 9292767
3. Greco, A.V. et al. 1997. Clin. Chim. Acta. 258(2): 209-218. PMID: 9074817
4. Greco, A.V. et al. 1998. Nutrition. 14(4): 351-357. PMID: 9591306

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