Geldanamycin is an ansamycin consisting of a 19-membered macrocyle incorporating a benzoquinone ring and a lactam functionality. It shows antimicrobial activity against many Gram-positive and some Gram-negative bacteria. It has a role as an antiviral agent, an antineoplastic agent, an antimicrobial agent, a cysteine protease inhibitor and a Hsp90 inhibitor.
CAT No: MFP-021
CAS No:30562-34-6
Synonyms/Alias:UNII-Z3K3VJ16KU; CHEBI:5292; Z3K3VJ16KU
Chemical Name:[(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
3. Low bone turnover and low BMD in Down syndrome: effect of intermittent PTH treatment
5. The spatiotemporal control of signalling and trafficking of the GLP-1R
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