H-Arg(Mtr)-OH

H-Arg(Mtr)-OH is a protected arginine amino acid derivative bearing a methyltrityl (Mtr) group on the side-chain guanidinium functionality, with a free α-amino group and a free α-carboxylic acid (as the hydrochloride-free "-OH" form) suitable for peptide-related chemistry. The arginine backbone provides the characteristic guanidinium side chain, while N-terminal protection is absent in the name and the Mtr group functions as a chemoselective protection element that suppresses side-chain guanidinium reactivity during coupling steps. In synthesis and chemical biology workflows, the molecule is used as a building block for incorporating arginine with controlled side-chain protection into peptides and peptide analogs, including solid-phase or solution-phase assembly where stepwise formation of amide bonds requires orthogonal functional-group management.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: CP00242

CAS No:80745-10-4

Synonyms/Alias:N-ω-4-methoxy-2,3,6-trimethylbenzenesulfonyl-L-arginine monohydrate;H-Arg(MTR)-OH;80745-10-4;(S)-2-Amino-5-(3-((4-methoxy-2,3,6-trimethylphenyl)sulfonyl)guanidino)pentanoicacid;ST51037650;N|O-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-D-arginine;Nomega-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;Npoundinvertedquestionmark(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;200114-52-9;PubChem6341;AC1OLQV8;N'-(4-Methoxy-2,3,6-trimethylbenzenesulfonyl)-L-arginine;75137_ALDRICH;75137_FLUKA;CTK8G1977;MolPort-003-983-962;ZINC2522598;CH-193;KM2042;AJ-90772;AK-81230;RT-014737;A7086;FT-0641774;ST24036005

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M.F/Formula

C16H26N4O5S

M.W/Mr.

404.5

Abbr

H-Arg(Mtr)-OH.H2O

InChI

1S/C16H26N4O5S/c1-9-8-13(25-4)10(2)11(3)14(9)26(23,24)20-16(18)19-7-5-6-12(17)15(21)22/h8,12H,5-7,17H2,1-4H3,(H,21,22)(H3,18,19,20)/t12-/m0/s1

InChI Key

FUSAEZSSVDNYPO-LBPRGKRZSA-N

Canonical SMILES

CC1=CC(=C(C(=C1S(=O)(=O)NC(=NCCCC(C(=O)O)N)N)C)C)OC

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