Lapatinib

Lapatinib is a dual-target small-molecule ligand widely used in biochemical studies of kinase signaling mechanisms. Its aromatic and heterocyclic groups support analyses of ATP-binding clefts and conformational dynamics. Researchers employ it to explore allosteric modulation within kinase domains. The compound aids structural and mechanistic investigations in receptor tyrosine kinase networks.

Designed for biological research and industrial applications, not intended for individual clinical or medical purposes.

CAT No: Z10-101-142

CAS No:231277-92-2

Synonyms/Alias:lapatinib;n-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine;4-Quinazolinamine, N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl]amino]methyl]-2-furanyl]-;Lapatinib(TINIBS);N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[(2-methylsulfonylethylamino)methyl]-2-furyl]quinazolin-4-amine;Lapatinib Base N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5

Custom Peptide Synthesis
cGMP Peptide
  • Registration of APIs
  • CMC information required for an IND
  • IND and NDA support
  • Drug master files (DMF) filing
M.F/Formula
C29H26ClFN4O4S
M.W/Mr.
581.0575432
Application
Lapatinib Ditosylate (GW572016, GW2016, Tykerb, Tyverb) is a potent EGFR and ErbB2 inhibitor with IC50 of 10.8 and 9.2 nM, respectively. Anti-tumor.

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